• Values are average percent change from baseline
  • Data is from pooled results of 4 placebo-controlled trials
  • Average baseline value in both groups: Total - 307 mg/dl; LDL - 214 mg/dl;
    Triglycerides - 191 mg/dl; HDL - 52 mg/dl
  • Reference [1]
Fenofibrate at recommended dosing for 3 - 6 months
Fenofibrate
(N=361)
Placebo
(N=285)
Total -19% 0%
LDL -21% -2%
Triglycerides -29% +8%
HDL +11% +1%

  • Values are average percent change from baseline
  • Average baseline value in both groups: Total ∼ 267 mg/dl; LDL ∼ 101 mg/dl;
    Triglycerides ∼ 718 mg/dl; HDL ∼ 28 mg/dl
  • Reference [1]
Fenofibrate at recommended dosing for 8 weeks
Fenofibrate
(N=48)
Placebo
(N=44)
Total -14% 0%
LDL +45% -4%
Triglycerides -55% +7%
HDL +23% +5%



  • Fenofibrate dosed at maximum recommended daily doses
  • Reference [1]
Abnormal liver enzymes
(% of patients)
Fenofibrates
(N=439)
Placebo
(N=365)
7.5% 1.4%